Influence of rosmarinic acid and Salvia officinalis extracts on melanogenesis of B16F10 cells

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Rosmarinic Acid and Melissa officinalis Extracts Differently Affect Glioblastoma Cells

Lemon balm (Melissa officinalis L.) has many biological effects but especially important is its neuroprotective activity. The aim of the study is to produce different extracts of Melissa officinalis and analyse their chemical composition and biological properties on rat glioblastoma C6 cells. Results revealed that rosmarinic acid (RA) is the predominant compound of lemon balm extracts. RA has c...

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Permeability of rosmarinic acid in Prunella vulgaris and ursolic acid in Salvia officinalis extracts across Caco-2 cell monolayers.

ETHNOPHARMACOLOGICAL RELEVANCE Rosmarinic acid (RA), a caffeic acid-related compound found in high concentrations in Prunella vulgaris (self-heal), and ursolic acid (UA), a pentacyclic triterpene acid concentrated in Salvia officinalis (sage), have been traditionally used to treat inflammation in the mouth, and may also be beneficial for gastrointestinal health in general. AIM OF THE STUDY To...

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Radiosensitizing effect of rosmarinic acid in metastatic melanoma B16F10 cells.

BACKGROUND Rosmarinic acid is an ester of caffeic acid with interesting biological activities including antioxidant effects and scavenging of oxygen-free radicals. AIM To determine the potentially paradoxical effect of rosmarinic acid, typically being radioprotective when applied to non-tumorous cells, yet conversely displaying a sensitizing action when applied to metastatic B16F10 melanoma c...

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Establishment of Salvia officinalis L. hairy root cultures for the production of rosmarinic acid.

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ژورنال

عنوان ژورنال: Revista Brasileira de Farmacognosia

سال: 2013

ISSN: 0102-695X

DOI: 10.1590/s0102-695x2012005000135